Breast cancer in men has traditionally been reported to have a worse prognosis than
breast cancer in women. Such conclusion was based on the later stage at diagnosis
as well as older age commonly observed in men with breast cancer. Lack of early detection
and disparities in treatment were believed to be responsible for worse outcomes. Several
earlier studies reported similar stage-specific survival when comparing male to female
breast cancer. Hence, the consensus was that male and female breast cancer were biologically
similar, and that gender should not be considered a predictor of survival apart from
stage of presentation and patient age. One study further suggested improved disease-specific
survival in male breast cancer.
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References
- Men with breast cancer have better disease-specific survival than women.Arch Surg. 2004; 139: 1079-1082https://doi.org/10.1001/archsurg.139.10.1079
- Poorer survival outcomes for male breast cancer compared with female breast cancer may be attributable to in-stage migration.Ann Surg Oncol. 2011; 18: 1837-1844https://doi.org/10.1245/s10434-010-1468-3
- Overall mortality after diagnosis of breast cancer in men vs women.JAMA Oncol. 2019; 5: 1589-1596https://doi.org/10.1001/jamaoncol.2019.2803
- Gender disparity in breast cancer: a veteran population-based comparison.Clin Breast Cancer. 2021; https://doi.org/10.1016/j.clbc.2021.01.013
Article info
Publication history
Published online: July 20, 2021
Accepted:
May 23,
2021
Received:
May 17,
2021
Identification
Copyright
© 2021 Elsevier Inc. All rights reserved.
