Abstract
Background
There is little information on the oncological outcomes of breast-conserving surgery
(BCS) with immediate reconstruction using a latissimus dorsi myocutaneous flap (LDMF)
for breast cancer compared with BCS alone.
Patients and Methods
We conducted a retrospective cohort study from a single institution comparing the
margin positivity rates after initial surgery, re-excision rates, and local recurrence
(LR) between BCS with immediate LDMF reconstruction (n = 145) and BCS alone (n = 1040)
performed from 2012 to 2017 for newly diagnosed stage 0-3 breast cancer.
Results
The positive rates of surgical margin after initial surgery were significantly lower
in the BCS with LDMF group than in the BCS alone group (4.1 vs. 10.8%; P = .006). There were no marked differences in the re-excision rates between the BCS with
LDMF and BCS alone groups (P = .1). At a median follow-up of 61 months, the surgical method (BCS with LD vs. BCS alone)
was not associated with the LR-free survival after adjusting for various clinicopathologic
factors (P = .8).
Conclusion
Our findings suggest that BCS with immediate LDMF reconstruction is oncologically
safe for breast cancer compared with BCS alone. However, further studies are needed.
Keywords
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Article info
Publication history
Published online: June 14, 2021
Accepted:
June 9,
2021
Received in revised form:
June 8,
2021
Received:
May 13,
2021
Identification
Copyright
© 2021 Elsevier Inc. All rights reserved.
