- •Four percent of contrast enhanced mammography examinations contained an enhancing finding seen only on subtraction images, ie, without low energy mammographic or sonographic correlate.
- •Twenty percent of enhancing findings seen only on subtraction images were downgraded to benign after undergoing correlative MR.
- •Twenty six percent of enhancing findings seen only on subtraction images that underwent biopsy were malignant on pathology.
- •Image-guided tissue biopsy should be considered for enhancing findings seen only on subtraction images, using either CEM or MR guidance.
Materials and methods
Abbreviations:CEM (Contrast-Enhanced Mammography), MRI (Magnetic Resonance Imaging), PPV (Positive Predictive Value), MR-VABB (MR-guided vacuum-assisted breast biopsy), NME (non-mass enhancement), CAD (computer assisted device), BI-RADS (Breast Imaging Radiology and Data Systems)
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