ABSTRACT
Genomic platforms have proven to be more accurate as a prognostic tool than immunohistochemistry
studies in patients with early, hormone receptor positive, HER 2 negative breast cancer
and, in some cases, have also demonstrated predictive ability for chemotherapy benefit.
They are now widely applied in node-negative disease, but their use in node-positive
disease is more recent and more controversial, especially in premenopausal patients.
In this article, we review the use of these tests in node-positive disease.
Key words
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Article Info
Publication History
Accepted:
July 24,
2022
Received in revised form:
July 12,
2022
Received:
March 23,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2022 Elsevier Inc. All rights reserved.